Facile hydrothermal synthesis of NiTe nanorods for non-enzymatic electrochemical sensing of whole blood hemoglobin in pregnant anemic women.

Electrochemical sensing methods monitor biomolecules because of their specificity, rapid response, lower cost, and automation. Hemoglobin is an abundant protein in the human body and is correlated with various physiological processes. Levels of hemoglobin in blood are associated with anemia in pregnant women. In this research, a non-enzymatic sensor based on NiTe nanorods is developed for the detection and quantification of hemoglobin (Hb) from anemic pregnant patients. NiTe nanorods are synthesized by the single-step method. After characterizing the material, sensing parameters such as the effect of scan rate, pH, concentration, and interferences are optimized using standard hemoglobin samples. Linearity, the limit of detection (LOD), and the limit of quantification (LOQ) for NiTe nanorods are 0.99698, 0.012 nM, and 0.04 nM, respectively. Stability is measured by cyclic chronoamperometry (12 h) and voltammetry (100 cycles). Recovery of hemoglobin from blood samples is in the range of 63-90%. NiTe nanorods quantitatively determine hemoglobin from the blood samples of anemic pregnant women.

Leiomyomatosis peritonealis disseminata: An exceptional case.

Leiomyomatosis peritonealis disseminata is a rare clinical disorder characterised by proliferation of smooth muscles spread all over the peritoneal cavity. History and examination do not help in establishing a proper diagnosis, which is possible only by histopathology. Although LPD is a benign disease which regresses spontaneously, it may degenerate to malignancy, so proper follow up is mandatory. A 38-year-old lady presented with lower abdominal pain on 27th day of her menstrual cycle. Due to suspicion of ovarian cyst accident, laparotomy was performed during which innumerable nodules were found scattered all over the peritoneal cavity. Histopathology revealed leiomyomatosis peritonealis disseminata. The patient was followed up for two years without any treatment and she remained asymptomatic.

Maternal and foetal outcome in gestational diabetes.

BACKGROUND: Gestational diabetes is impaired carbohydrate metabolism first diagnosed in pregnancy. Knowledge of diabetes dates back to centuries before Christ. Objective was to describe maternal complications during antenatal period and Maternal and neonatal outcome in gestational diabetes mellitus. METHODS: This Descriptive observational study was conducted at Department of Obstetrics and Gynaecology, Alhada Military Hospital, Taif, KSA. It was done during January-December 2009 to measure maternal and neonatal outcome. Hundred pregnant women diagnosed through glucose tolerance test as diabetic were enrolled as study subjects. All the subjects were enrolled and followed regularly at Obstetric and Gynaecology out-patient Department of Alhada Military Hospital, Taif. Blood glucose level was controlled either by diet or by diet and insulin. Study subjects were hospitalised for adjustment of dose of insulin and for management of complications. Foetal well being was assessed by kick count, cardiotocography and ultrasound. Time and mode of delivery was decided at 36 week of gestation. Intra-partum maternal blood glucose level was monitored and foetal monitoring was done by cardiotocography. RESULTS: Total numbers of women delivered were 2,858. Hundred cases of diabetes mellitus during pregnancy were studied. Eighty-eight patients were above 25 years of age, multiparous ladies with gestational diabetes in 76% of cases. Insulin was required in 64% of patients. Polyhydramnios was most common maternal complication. Two out of 100 had spontaneous miscarriage; 14 underwent preterm delivery while 84 reached term with two intrauterine death. Caesarean section was carried out in 58 patients. Total number of babies delivered alive were 92. There were 4 neonatal deaths. Hyperbilirubinemia was the most common neonatal complication. CONCLUSION: It was concluded that early detection, constant supervision, strict glycaemic control, delivery with intensive intrapartum monitoring and facilities of expert neonatologist can result in good maternal and foetal outcome, without much morbidity.